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ChemicalBook--->CAS DataBase List--->1809413-98-6

1809413-98-6

1809413-98-6 Structure

1809413-98-6 Structure
IdentificationBack Directory
[Name]

Wnt/β-catenin-IN-3
[CAS]

1809413-98-6
[Synonyms]

Wnt/β-catenin-IN-3
[Molecular Formula]

C26H23NO7
[MOL File]

1809413-98-6.mol
[Molecular Weight]

461.46
Chemical PropertiesBack Directory
[Melting point ]

179.7 °C
[Boiling point ]

609.6±55.0 °C(predicted)
[density ]

1.302±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

13.58±0.70(predicted)
Hazard InformationBack Directory
[Uses]

Wnt/β-catenin-IN-3 (compound 17) is a Wnt/β-catenin inhibitor with low micromolarGI50s against various cancer cells. Wnt/β-catenin-IN-3triggers G2/M cell cycle arrest though activation of p53-p21 pathway as well as intrinsic and extrinsic apoptotic death of colon cancer cells[1].
[References]

[1] Hassan AHE, et al. Discovery of a stilbenoid-flavanone hybrid as an antitumor Wnt/β-catenin signaling pathway inhibitor. Bioorg Chem. 2024 Apr;145:107178. DOI:10.1016/j.bioorg.2024.107178
1809413-98-6 suppliers list
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