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ChemicalBook--->CAS DataBase List--->1807530-14-8

1807530-14-8

1807530-14-8 Structure

1807530-14-8 Structure
IdentificationBack Directory
[Name]

2-HYDROXY-N-[2-(1H-INDOL-3-YL)ETHYL]BENZAMIDE
[CAS]

1807530-14-8
[Synonyms]

STP
N-SALICYLOYLTRYPTAMINE
2-HYDROXY-N-[2-(1H-INDOL-3-YL)ETHYL]BENZAMIDE
2,3,5,6-tetrafluoro-4-(pent-4-ynoyloxy)benzenesulfonic acid, sodium salt
[Molecular Formula]

C11H7F4NaO5S
[MDL Number]

MFCD06798353
[MOL File]

1807530-14-8.mol
[Molecular Weight]

350.22
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: ~26 mg/mL
[form ]

solid
[color ]

white
[Appearance]

colorless solid
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Description]

This water soluble alkyne activated ester reagent is used for the attachment of alkyne group to variois biomolecules such as proteins, and peptides. Amino-DNA, and other amines can be used as well. Since natural proteins do not contain alkynes, but almost always contain amines (lysines), this molecule is an "adaptor" to turn natural amines into alkynes.


Use this product to enable any of your proteins for click chemistry.


This is an STP (sulfotetrafluorophenyl) ester. STP esters are similar to NHS esters, but possess higher hydrophilicity, and water solubility. It works fine in pure aqueous reactions without addition of organic co-solvent, and is best suited for the modification of proteins.

[Uses]

Pentynoic acid STP ester sodium is a click chemistry reagent containing a terminal propargyl group and a STP ester group. Pentynoic acid STP ester sodium is suitable for protein modification[1].
[References]

[1] Brian J. FILANOSKI, et al. Methods of purifying antibody-nucleic acid conjugates. WO2023212135A1.
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