Identification | Back Directory | [Name]
m-PEG5-phosphonic acid | [CAS]
1807512-39-5 | [Synonyms]
m-PEG5-phosphonic acid Phosphonic acid, P-3,6,9,12,15-pentaoxahexadec-1-yl- | [Molecular Formula]
C11H25O8P | [MDL Number]
MFCD28505503 | [MOL File]
1807512-39-5.mol | [Molecular Weight]
316.29 |
Hazard Information | Back Directory | [Description]
m-PEG5-phosphonic acid ethyl ester is a PEG chain linker. The hydrophilic PEG linkers increase the water solubility of compound in aqueous media. Longer PEG chains have better water solubility properties relative to shorter PEG chains. | [Uses]
m-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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