| Identification | Back Directory | [Name]
endo-BCN-PEG4-t-butyl ester | [CAS]
1807501-83-2 | [Synonyms]
endo-BCN-PEG4-Boc
endo-BCN-PEG4-CH2CH2COOtBu
endo-BCN-PEG4-t-butyl ester | [Molecular Formula]
C26H43NO8 | [MDL Number]
MFCD28505580 | [MOL File]
1807501-83-2.mol | [Molecular Weight]
497.62 |
| Chemical Properties | Back Directory | [Boiling point ]
594.3±45.0 °C(Predicted) | [density ]
1.13±0.1 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DCM, DMF | [pka]
12.05±0.46(Predicted) |
| Hazard Information | Back Directory | [Description]
endo-BCN-PEG4-t-butyl ester is a click chemistry linker containing a BCN group and a t-butyl protected carboxyl group. The BCN group can react with azide-tagged molecules. The protected carboxyl group (COOH) prevents self coupling or polymerization under standard acid/amine or acid/hydroxyl coupling conditions. The t-butyl ester can be converted to free acid under acidc condition. | [Uses]
endo-BCN-PEG4-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | [IC 50]
PEGs; Alkyl/ether |
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