| Identification | Back Directory | [Name]
4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE | [CAS]
178803-51-5 | [Synonyms]
SNC 162
4-[(S)-[(2S,5R)-2,5-DIMETHYL-4-(2-PROPENYL)-1-PIPERAZINYL]PHENYLMETHYL]-N,N-DIETHYLBENZAMIDE
4-[(S)-[(2S,5R)-2,5-Dimethyl-4-(2-propen-1-yl)-1-piperazinyl]phenylmethyl]-N,N-diethylbenzamide | [Molecular Formula]
C27H37N3O | [MDL Number]
MFCD04307698 | [MOL File]
178803-51-5.mol | [Molecular Weight]
419.6 |
| Chemical Properties | Back Directory | [Boiling point ]
536.4±50.0 °C(Predicted) | [density ]
1.027 | [storage temp. ]
Store at RT | [solubility ]
Soluble to 100 mM in 1eq. HCl | [form ]
Powder | [pka]
7.28±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Opioid agonists exert a broad range of effects on the immune system ranging from inflammatory response modulation to opioid and chemokine receptor expression. SNC 162 is a selective δ-opioid receptor agonist. | [Definition]
ChEBI:4-[(S)-[(2S,5R)-2,5-dimethyl-4-prop-2-enyl-1-piperazinyl]-phenylmethyl]-N,N-diethylbenzamide is a diarylmethane. | [Biological Activity]
Potent and selective non-peptide δ -opioid receptor agonist (K i = 0.63 nM). Displays > 8000-fold selectivity over μ -opioid receptors and is centrally active following systemic administration in vivo . | [IC 50]
δ Opioid Receptor/DOR | [storage]
Store at RT |
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