Identification | Back Directory | [Name]
1-Propanesulfonamide, 2,2-dimethyl-3-[[7-(1-methylethyl)[1,2,4]triazolo[1,5-b]pyridazin-6-yl]oxy]- | [CAS]
175215-34-6 | [Synonyms]
1-Propanesulfonamide, 2,2-dimethyl-3-[[7-(1-methylethyl)[1,2,4]triazolo[1,5-b]pyridazin-6-yl]oxy]- | [Molecular Formula]
C13H21N5O3S | [MOL File]
175215-34-6.mol | [Molecular Weight]
327.4 |
Hazard Information | Back Directory | [Uses]
TAK-661 is a inhibitor of eosinophil chemotaxis. TAK-661 significantly reduces the bronchoconstriction during the late phase, along with the inhibition of eosinophilia in bronchoalveolar lavage (BAL) and the eosinophil infiltration into the airway wall[1]. | [References]
[1] K Fujimoto, et al. Effects of an eosinophil chemotaxis inhibitor, TAK-661, on antigen-induced asthmatic responses in allergic sheep. Lung. 2002;180(3):161-72. DOI:10.1007/s004080000090 |
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