Identification | Back Directory | [Name]
5'-O-(4,4'-Dimethoxytrityl)-2,2'-anhydro-D-uridine | [CAS]
173170-12-2 | [Synonyms]
2,2'-Anhydro-5'-O-DMT-uridine 5'-O-(4,4'-Dimethoxytrityl)-2,2'-anhydro-D-uridine 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-2,3,3a,9a-tetrahydro-3-hydroxy-, (2R,3R,3aS,9aR)- | [Molecular Formula]
C30H28N2O7 | [MOL File]
173170-12-2.mol | [Molecular Weight]
528.55 |
Hazard Information | Back Directory | [Uses]
5'-Protected 2,2'-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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