| Identification | Back Directory | [Name]
3-AMINO-6-BROMOPYRAZINE-2-CARBONITRILE | [CAS]
17231-51-5 | [Synonyms]
2-AMINO-5-BROMO-3-CYANOPYRAZINE
2-Amino-3-cyano-5-bromopyrazine
3-AMINO-6-BROMOPYRAZINE-2-CARBONITRILE
2-Pyrazinecarbonitrile, 3-amino-6-bromo-
3-Amino-6-bromopyrazine-2-carbonitrile 98%
3-AMINO-6-BROMOPYRAZINE-2-CARBONITRILE, 95+%
3-AMINO-6-BROMOPYRAZINE-2-CARBONITRILE ISO 9001：2015 REACH | [Molecular Formula]
C5H3BrN4 | [MDL Number]
MFCD06658300 | [MOL File]
17231-51-5.mol | [Molecular Weight]
199.01 |
| Chemical Properties | Back Directory | [Melting point ]
183-184 °C(Solv: benzene (71-43-2)) | [Boiling point ]
341.0±42.0 °C(Predicted) | [density ]
1.94±0.1 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [pka]
-0.11±0.10(Predicted) | [Appearance]
Light yellow to yellow Solid |
| Hazard Information | Back Directory | [Synthesis]
Bromine (0.95 mL, 19 mmol) was added slowly and dropwise to a solution of 3-aminopyrazine-2-carbonitrile (1.7 g, 14 mmol) in acetic acid (40 mL) at room temperature. The reaction mixture was heated to 60 °C and held for 30 min, followed by cooling to room temperature. The mixture was poured into ice water and the precipitated solid was collected by filtration. After sufficient washing with water, 3-amino-6-bromopyrazine-2-carbonitrile was obtained as a yellow solid (2.3 g, 83% yield). The product was characterized by 1H NMR (500 MHz, DMSO-d6): δ 8.44 (s, 1H), 7.60 (br s, 2H). Mass spectrum (ES+): m/z 199 (M+H)+. | [References]
[1] Journal of Organic Chemistry, 1987, vol. 52, # 18, p. 3997 - 4000
[2] Patent: US2007/259876, 2007, A1. Location in patent: Page/Page column 18 |
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