| Chemical Properties | Back Directory | [Boiling point ]
2094.0±65.0 °C(predicted) | [density ]
1.311±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
3.08±0.10(predicted) | [Sequence]
Val-Leu-Gln-Trp-Ala-Lys-Lys-Gly-Tyr-Tyr-Thr-Met-Lys-Ser-Asn |
| Hazard Information | Back Directory | [Uses]
KGYY15 (Mouse KGYY15) is a CD40 targeting peptide, which weakly inhibits the CD40-CD40L interaction with IC50 of more than 1mM. KGYY15 activates 33% NF-κB pathway at 100 μM[1]. | [References]
[1] Bojadzic D, et al., CD40-targeting KGYY15 peptides do not efficiently block the CD40-CD40L interaction. Diabetologia. 2019 Nov;62(11):2158-2160. DOI:10.1007/s00125-019-04996-6 |
|
|