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ChemicalBook--->CAS DataBase List--->1676104-75-8

1676104-75-8

1676104-75-8 Structure

1676104-75-8 Structure
IdentificationBack Directory
[Name]

Hepcidin 1 (Mouse)
[CAS]

1676104-75-8
[Synonyms]

Hepcidin 1 (Mouse)
[Molecular Formula]

C111H169N31O35S8
[MOL File]

1676104-75-8.mol
[Molecular Weight]

2754.24
Chemical PropertiesBack Directory
[Boiling point ]

2726.8±65.0 °C(Predicted)
[density ]

1.49±0.1 g/cm3(Predicted)
[Sequence]

H-Asp-Thr-Asn-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Lys-Cys-Cys-Asn-Asn-Ser-Gln-Cys-Gly-Ile-Cys-Cys-Lys-Thr-OH trifluoroacetate salt
Hazard InformationBack Directory
[Uses]

Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion. Hepcidin-1 (mouse) downregulates the level of FPN1 protein and increases intracellular iron. Hepcidin-1 (mouse) facilitates osteoclast differentiation[1].
[IC 50]

MMP-9; cathepsin K
[References]

[1] Zhao GY, et al. Effects of mouse hepcidin 1 treatment on osteoclast differentiation and intracellular iron concentration. Inflammation. 2015 Apr;38(2):718-27. DOI:10.1007/s10753-014-9982-2
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