| Identification | Back Directory | [Name]
H-L-CYS(TRT)-NH2 HCL | [CAS]
166737-85-5 | [Synonyms]
L-Cys(Trt)-NH2
H-L-Cys(Trt)-NH2
H-Cys(Trt)-NH2.HCl
H-L-CYS(TRT)-NH2 HCL
H-Cys(Trt)-NH2
H-Cys(Trt)-NH2（non-animal）
S-Trityl-L-cysteinamide,98%
S-Trityl-L-cysteinaMide, 98%
H-L-CYS(TRT)-NH2 HCL USP/EP/BP
S-Trityl-L-cysteinamide hydrochloride
S-Trityl-L-cysteine amide≥ 98% (HPLC)
(R)-2-Amino-3-(tritylthio)propanamide
S-TRITYL-L-CYSTEINE AMIDE HYDROCHLORIDE
(2R)-2-amino-3-tritylsulfanylpropanamide
(2R)-2-Amino-3-[(triphenylmethyl)thio]propanamide
(R)-2-amino-3-(tritylthio)propanamide hydrochloride
PropanaMide,2-aMino-3-[(triphenylMethyl)thio]-, (2R)-
(2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanamide | [Molecular Formula]
C22H23ClN2OS | [MDL Number]
MFCD08274533 | [MOL File]
166737-85-5.mol | [Molecular Weight]
398.95 |
| Chemical Properties | Back Directory | [Boiling point ]
543.2±50.0 °C(Predicted) | [density ]
1.203±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
15.83±0.50(Predicted) | [color ]
Off-white |
| Hazard Information | Back Directory | [Chemical Properties]
White to off-white powder | [Uses]
(2R)-2-Amino-3-[(triphenylmethyl)thio]propanamide is a useful building block for organic synthesis. | [Synthesis]
General procedure for the synthesis of S-trityl-L-cysteamine from (9H-fluoren-9-yl)methyl (R)-(1-amino-1-oxo-3-(triphenylmethylthio)propan-2-yl)carbamate: (R)-(9H-fluoren-9-yl)methyl (1-amino-1-oxo-3-(triphenylmethylthio)propan-2-yl)carbamate (4 g. 6.84 mmol) was dissolved in N,N-dimethylformamide (20 mL), piperidine (0.14 mL, 1.368 mmol) was added and the reaction was carried out for 4 h at room temperature. The progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was washed with saturated aqueous sodium chloride solution and subsequently extracted with dichloromethane. The organic phase was dried with anhydrous sodium sulfate, concentrated and purified by column chromatography (eluent: methanol/dichloromethane, 1%-5% gradient) to afford the title product S-trityl-L-cysteamine as a yellow oil (2.3 g, yield: 92%). | [References]
[1] Patent: CN106432014, 2017, A. Location in patent: Paragraph 0079; 0083; 0084; 0085; 0119; 0123; 0124; 0125
[2] Patent: WO2008/116302, 2008, A1. Location in patent: Page/Page column 43-44 |
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