| Identification | Back Directory | [Name]
Epiblastin A | [CAS]
16470-02-3 | [Synonyms]
Epiblastin A
Epiblastin A NEW
Epiblastin A - Bio-X
Triamterene Impurity 8
Epiblastin A >=98% (HPLC)
6-(3-chlorophenyl)pteridine-2,4,7-triamine
6-(3-Chlorophenyl)-2,4,7-pteridinetriamine | [Molecular Formula]
C12H10ClN7 | [MOL File]
16470-02-3.mol | [Molecular Weight]
287.71 |
| Chemical Properties | Back Directory | [Melting point ]
353 °C | [Boiling point ]
596.1±60.0 °C(Predicted) | [density ]
1.593±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:5.75(Max Conc. mg/mL);19.99(Max Conc. mM) | [form ]
A crystalline solid | [pka]
6.24±0.10(Predicted) | [color ]
Light yellow to green yellow | [InChI]
InChI=1S/C12H10ClN7/c13-6-3-1-2-5(4-6)7-9(14)18-11-8(17-7)10(15)19-12(16)20-11/h1-4H,(H6,14,15,16,18,19,20) | [InChIKey]
ZWNKKZSRANLVEW-UHFFFAOYSA-N | [SMILES]
N1=C2C(N=C(C3=CC=CC(Cl)=C3)C(N)=N2)=C(N)N=C1N |
| Hazard Information | Back Directory | [Uses]
Epiblastin A is triamterene derivative that potently induces reprograming of epiblast stem cells (EpiSC) into embryonic stem cells (ESC). Epiblastin A is a potent reversible inhibitor of casein kinase 1 (CK1) α, δ, and ε that binds to ATP-binding site. | [Biological Activity]
Epiblastin A is triamterene derivative th at potently induces reprograming of epiblast stem cells (EpiSC) into embryonic stem cells (ESC). Epiblastin A is a potent reversible inhibitor of casein kinase 1 (CK1) αδand ε th at binds to ATP-binding site. | [storage]
Store at -20°C |
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