Identification | Back Directory | [Name]
Ianthelliformisamine C TFA salt | [CAS]
1643593-30-9 | [Synonyms]
IanthelliformisamineC TFA Ianthelliformisamine-C TFA Ianthelliformisamine C TFA Ianthelliformisamine C TFA salt | [Molecular Formula]
C32H39Br4F3N4O6 | [MOL File]
1643593-30-9.mol | [Molecular Weight]
952.3 |
Hazard Information | Back Directory | [Description]
Ianthelliformisamine C TFA is an antibiotic enhancer against resistant Gram-negative bacteria. | [Uses]
Ianthelliformisamine C ditrifluoroacetate is an antibiotic enhancer with activity against resistant Gram-negative bacteria. Ianthelliformisamine C ditrifluoroacetate has been shown to improve the efficacy of doxycycline against Pseudomonas aeruginosa. Ianthelliformisamine C ditrifluoroacetate was prepared using peptide coupling, resulting in high chemical yields of 27 to 91%. Ianthelliformisamine C ditrifluoroacetate exhibits its mechanism of action by inducing ATP efflux and causing membrane depolarization in bacterial cells. | [References]
[1] New Ianthelliformisamine derivatives as antibiotic enhancers against resistant Gram-negative bacteria DOI:10.1021/jm500194e |
|
|