Identification | Back Directory | [Name]
Benzamide, N-(2-aminophenyl)-4-[2-[4-(dimethylamino)phenyl]diazenyl]- | [CAS]
1628784-50-8 | [Synonyms]
BG14 BG-14 BG 14 Benzamide, N-(2-aminophenyl)-4-[2-[4-(dimethylamino)phenyl]diazenyl]- | [Molecular Formula]
C21H21N5O | [MOL File]
1628784-50-8.mol | [Molecular Weight]
359.42 |
Hazard Information | Back Directory | [Description]
BG14 is a probe for chemo-optical modulation of epigenetically regulated transcription (COMET). It enables high-resolution, optical control of epigenetic mechanisms and photochromically inhibits human histone deacetylases using visible light. | [Uses]
BG14 is a chemical optical modulation of epigenetic regulation of transcription (COMET) probe. BG14 enables high-resolution optical control of epigenetic mechanisms using visible light and can photochromically inhibit human histone deacetylases (HDACs). BG14 can be used to study the dynamic regulation of the human genome[1]. | [References]
[1] Reis S A, et al. Light-controlled modulation of gene expression by chemical optoepigenetic probes[J]. Nature chemical biology, 2016, 12(5): 317-323. DOI:10.1038/nchembio.2042 |
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