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ChemicalBook--->CAS DataBase List--->1628784-50-8

1628784-50-8

1628784-50-8 Structure

1628784-50-8 Structure
IdentificationBack Directory
[Name]

Benzamide, N-(2-aminophenyl)-4-[2-[4-(dimethylamino)phenyl]diazenyl]-
[CAS]

1628784-50-8
[Synonyms]

BG14
BG-14
BG 14
Benzamide, N-(2-aminophenyl)-4-[2-[4-(dimethylamino)phenyl]diazenyl]-
[Molecular Formula]

C21H21N5O
[MOL File]

1628784-50-8.mol
[Molecular Weight]

359.42
Chemical PropertiesBack Directory
[Boiling point ]

517.5±45.0 °C(Predicted)
[density ]

1.18±0.1 g/cm3(Predicted)
[pka]

12.46±0.70(Predicted)
Hazard InformationBack Directory
[Description]

BG14 is a probe for chemo-optical modulation of epigenetically regulated transcription (COMET). It enables high-resolution, optical control of epigenetic mechanisms and photochromically inhibits human histone deacetylases using visible light.
[Uses]

BG14 is a chemical optical modulation of epigenetic regulation of transcription (COMET) probe. BG14 enables high-resolution optical control of epigenetic mechanisms using visible light and can photochromically inhibit human histone deacetylases (HDACs). BG14 can be used to study the dynamic regulation of the human genome[1].
[References]

[1] Reis S A, et al. Light-controlled modulation of gene expression by chemical optoepigenetic probes[J]. Nature chemical biology, 2016, 12(5): 317-323. DOI:10.1038/nchembio.2042
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