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ChemicalBook--->CAS DataBase List--->1621169-52-5

1621169-52-5

1621169-52-5 Structure

1621169-52-5 Structure
IdentificationBack Directory
[Name]

Myostatin inhibitory peptide 7
[CAS]

1621169-52-5
[Synonyms]

Myostatin inhibitory peptide 7
ACE-031Myostatininhibitorypeptide7
[Molecular Formula]

C133H227N43O33
[MOL File]

1621169-52-5.mol
[Molecular Weight]

2956.49
Chemical PropertiesBack Directory
[density ]

1.44±0.1 g/cm3(Predicted)
[form ]

Solid
[color ]

White to off-white
[InChIKey]

HXWLNPUQPASIHW-OOXKGWPCSA-N
Hazard InformationBack Directory
[Uses]

Myostatin inhibitory peptide 2 (compd 2) is a myostatin inhibitor with a Kd of 35.9 nM. Myostatin inhibitory peptide 2 can be used for researches of muscle atrophic disorders[1].
[in vivo]

Myostatin inhibitory peptide 2 (0.75 mM, 40 μL, i.m., once every two weeks for 4 weeks) increases the muscle weight of skeletal muscles in muscular dystrophy model mice[1].

[References]

[1] Takayama K, et al. Identification of the minimum peptide from mouse myostatin prodomain for human myostatin inhibition. J Med Chem. 2015 Feb 12;58(3):1544-9. DOI:10.1021/jm501170d
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