| Identification | Back Directory | [Name]
4-Quinolinecarboxamide, 2-(4-fluorophenyl)-N-[2-(methylamino)ethyl]- | [CAS]
1594427-18-5 | [Synonyms]
Viral 2C protein inhibitor 1
4-Quinolinecarboxamide, 2-(4-fluorophenyl)-N-[2-(methylamino)ethyl]- | [Molecular Formula]
C19H18FN3O | [MOL File]
1594427-18-5.mol | [Molecular Weight]
323.36 |
| Hazard Information | Back Directory | [Uses]
Viral 2C protein inhibitor 1 (compound 6aw) is a potent and broad-spectrum enterovirus antiviral agent, inhibiting viral 2C protein. Viral 2C protein inhibitor 1 inhibits multiple strains of EV-D68, EV-A71 and CVB3 with EC50s of 0.1~3.6 μM, and exhibits high selectivity index and relatively low cytotoxicity[1]. | [References]
[1] Musharrafieh R, et al. Development of broad-spectrum enterovirus antivirals based on quinoline scaffold. Bioorg Chem. 2020 Aug;101:103981. DOI:10.1016/j.bioorg.2020.103981 |
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