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ChemicalBook--->CAS DataBase List--->158798-83-5

158798-83-5

158798-83-5 Structure

158798-83-5 Structure
IdentificationBack Directory
[Name]

AK 275
[CAS]

158798-83-5
[Synonyms]

AK 275
Carbamic acid, N-[(1S)-1-[[[(1S)-1-[(ethylamino)carbonyl]propyl]amino]carbonyl]-3-methylbutyl]
Carbamic acid, N-[(1S)-1-[[[(1S)-1-[(ethylamino)carbonyl]propyl]amino]carbonyl]-3-methylbutyl]-, phenylmethyl ester
[Molecular Formula]

C20H31N3O4
[MDL Number]

MFCD30726048
[MOL File]

158798-83-5.mol
[Molecular Weight]

377.48
Chemical PropertiesBack Directory
[Boiling point ]

624.4±50.0 °C(Predicted)
[density ]

1.092±0.06 g/cm3(Predicted)
[pka]

11.15±0.46(Predicted)
Hazard InformationBack Directory
[Description]

AK 275 is an inhibitor of calpain that prevents degradation of cytoskeletal and myelin proteins in spinal cord in vitro.
[Uses]

AK 275, a calpain inhibitor, exhibits neuroprotection activity. AK 275 can be used in the study for central nervous system trauma and ischemia[1].
[References]

[1] T James, et al. New inhibitors of calpain prevent degradation of cytoskeletal and myelin proteins in spinal cord in vitro. J Neurosci Res. 1998 Jan 15;51(2):218-22. DOI:10.1002/(SICI)1097-4547(19980115)51:2<218::AID-JNR10>3.0.CO;2-4
158798-83-5 suppliers list
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