Identification | Back Directory | [Name]
3-METHYL-2-((E)-3-[1-[3-(TRIMETHYLAMMONIO)PROPYL]-4(1H)-QUINOLINYLIDENE]-1-PROPENYL)-1,3-BENZOTHIAZOL-3-IUM DIIODIDE | [CAS]
157199-63-8 | [Synonyms]
TO-PRO 3 TWO-PRO? 3 To-pro 3 Iodide TO-PRO3 iodide salt QHNORJFCVHUPNH-UHFFFAOYSA-L TO PRO3 iodide,TO-PRO-3 iodide TWO-PRO 3 (equivalent to TO-PRO 3) *5 mM DMSO Solution* *CAS 157199-63-8* 3-Methyl-2-((E)-3-((E)-1-(3-(trimethylammonio)propyl)quinolin-4(1H)-ylidene)prop-1-en-1-yl)ben trimethyl-[3-[4-[3-(3-methyl-1,3-benzothiazol-2-ylidene)prop-1-enyl]quinolin-1-ium-1-yl]propyl]azanium QUINOLINIUM, 4-[3-(3-METHYL-2(3H)-BENZOTHIAZOLYLIDENE)-1-PROPENYL]-1-[3-(TRIMETHYLAMMONIO)PROPYL]-, DIIODIDE 3-METHYL-2-((E)-3-[1-[3-(TRIMETHYLAMMONIO)PROPYL]-4(1H)-QUINOLINYLIDENE]-1-PROPENYL)-1,3-BENZOTHIAZOL-3-IUM DIIODIDE 3-METHYL-2-((E)-3-[1-[3-(TRIMETHYLAMMONIO)PROPYL]-4(1H)-QUINOLINYLIDENE]-1-PROPENYL)-1,3-BENZOTHIAZOL-3-IUM DIIODIDE | [Molecular Formula]
C26H31I2N3S | [MDL Number]
MFCD07433932 | [MOL File]
157199-63-8.mol | [Molecular Weight]
671.42 |
Chemical Properties | Back Directory | [Melting point ]
>250 ℃ | [solubility ]
Soluble in dimethyl sulfoxide | [form ]
powder | [color ]
Red-brown | [Appearance]
blue solution | [ex/em]
642/661 nm | [ε(extinction coefficient)]
102000 cm?1M?1 | [λmax]
642 nm | [Φ(quantum yield)]
0.11 | [Biological Applications]
Nucleic acid hybridization; nucleic acid assay; detecting nucleic acids,cells,bacteria,bromodeoxyuridine incorporation,Human papilloma virus (HPV),pathogens; counting leukocytes |
Hazard Information | Back Directory | [Description]
TO-TAP-3 (Thiazole Red Monomer, also known as TO-PRO?-3) is a far-red fluorescent carbocyanine monomeric dye. TO-TAP-3 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits a significant fluorescence enhancement upon binding to dsDNA.
TO-TAP-3 has a bright fluorescence signal and low background. The dye is useful for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in microscopy. It may be used for monitoring of cell viability and dead cell detection in culture. The long-wavelength fluorescence of TO-TAP-3 is well separated from green and red fluorophores, which makes it ideal for multicolor fluorescence labeling experiments. | [Uses]
TO-PRO-3 iodide is a highly efficient blue fluorescent dye that can stain cytoplasm as a cell tracer. | [Definition]
ChEBI: An unsymmetrical C3 cyanine dye having benzothiazolium-2-yl and quinolinium-4-yl substituents. | [Abs/Em Maxima]
643 (complex)/658 (complex) nm |
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