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ChemicalBook--->CAS DataBase List--->152785-82-5

152785-82-5

152785-82-5 Structure

152785-82-5 Structure
IdentificationBack Directory
[Name]

Seco-Duocarmycin SA
[CAS]

152785-82-5
[Synonyms]

Seco-Duocarmycin SA
(S)-Seco-Duocarmycin SA
[Molecular Formula]

C25H24ClN3O7
[MDL Number]

MFCD29127463
[MOL File]

152785-82-5.mol
[Molecular Weight]

513.93
Chemical PropertiesBack Directory
[Boiling point ]

773.9±60.0 °C(Predicted)
[density ]

1.458±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Solid
[pka]

9.69±0.40(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

(S)-Seco-Duocarmycin SA is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates[1].
[storage]

Store at -20°C
[References]

[1] Tichenor MS, et al. Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity. J Am Chem Soc. 2007 Sep 5;129(35):10858-69. DOI:10.1021/ja072777z
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