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ChemicalBook--->CAS DataBase List--->150173-78-7

150173-78-7

150173-78-7 Structure

150173-78-7 Structure
IdentificationBack Directory
[Name]

Bodipy 576/589
[CAS]

150173-78-7
[Synonyms]

Bodipy 576/589
[Molecular Formula]

C16H14BF2N3O2
[MDL Number]

MFCD34470573
[MOL File]

150173-78-7.mol
[Molecular Weight]

329.11
Chemical PropertiesBack Directory
[solubility ]

good in DMF, DMSO
[form ]

Solid
[color ]

Brown to black
[Appearance]

dark colored solid
[InChI]

InChI=1S/C16H14BF2N3O2/c18-17(19)21-11(6-8-16(23)24)3-4-12(21)10-13-5-7-15(22(13)17)14-2-1-9-20-14/h1-5,7,9-10,20H,6,8H2,(H,23,24)
[InChIKey]

HEVJIRROVGECSJ-UHFFFAOYSA-N
[SMILES]

[F-][B+3]1(N2=C(C=CC2=CC2=CC=C(C3NC=CC=3)[N-]12)CCC(=O)[O-])[F-].[H+]
Hazard InformationBack Directory
[Description]

BDP 576/589, a boron dipyrromethene dye. This hydrophobic dye with emission in the orange spectrum range has high quantum yield and high molar extinction coefficient. It is suitable for experiments measuring fluorescence lifetime and fluorescence polarization. This fluorophore can be used whether in wide-field and confocal microscopy or in multiphoton microscopy because of its high two-photon absorption cross-section.


This derivative is a carboxylic acid (contains a free COOH-group). It can be used as a reference control and for conjugation with an amino group after activation with carbodiimides.

[Uses]

BODIPY 576/589 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells[1]. Maximum excitation/emission wavelength: 576/589 nm[1].
[References]

[1] Bing Tang, et al. Development of BODIPY Dyes With Versatile Functional Groups at 3,5-positions From Diacyl Peroxides via Cu(ii)-catalyzed Radical Alkylation. Chem Commun (Camb). 2019 Apr 16;55(32):4691-4694. DOI:10.1039/c9cc01602c
[Abs/Em Maxima]

580/592 nm
[Fluoresene quantum yield]

0.13
[Extinction Coefficient]

98000
[CF260]

0.32
[CF280]

0.35
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