Identification | Back Directory | [Name]
4H-Imidazo[4,5-b]pyridine, 7-methyl-2-propyl-4-[[2-[2-(2H-tetrazol-5-yl)phenyl]-6-benzothiazolyl]methyl]- | [CAS]
149760-98-5 | [Synonyms]
AS1134900 4H-Imidazo[4,5-b]pyridine, 7-methyl-2-propyl-4-[[2-[2-(2H-tetrazol-5-yl)phenyl]-6-benzothiazolyl]methyl]- | [Molecular Formula]
C25H22N8S | [MOL File]
149760-98-5.mol | [Molecular Weight]
466.56 |
Chemical Properties | Back Directory | [Boiling point ]
718.5±70.0 °C(Predicted) | [density ]
1.45±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
3.87±0.10(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
AS1134900 is a highly selective, allosteric and uncompetitive NADP+-dependent malic enzyme 1 (ME1) inhibitor[1]. | [References]
[1] Yoshida T, et al. Discovery and Characterization of a Novel Allosteric Small-Molecule Inhibitor of NADP+-Dependent Malic Enzyme 1. Biochemistry. 2022 Jul 12. DOI:10.1021/acs.biochem.2c00123 |
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