| Identification | Back Directory | [Name]
aspalatone | [CAS]
147249-33-0 | [Synonyms]
aspalatone
Aspalatone Exclusive
JVBIZYPCGNCWIT-UHFFFAOYSA-N
Benzoic acid, 2-(acetyloxy)-, 2-methyl-4-oxo-4H-pyran-3-yl ester | [Molecular Formula]
C15H12O6 | [MDL Number]
MFCD00871244 | [MOL File]
147249-33-0.mol | [Molecular Weight]
288.25 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml; Ethanol: 1 mg/ml | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Uses]
Aspalatone is an orally active antiplatelet aggregant with IC50 of 180 μM. Aspalatone has antioxidant and neuroprotective activities[1][2]. | [References]
[1] Han BH, et al. Synthesis and antiplatelet effects of the new antithrombotic agent aspalatone with low ulcerogenicity. Arzneimittelforschung. 1994 Oct;44(10):1122-6. PMID:7818584
[2] Kim HC, et al. Aspalatone, a new antiplatelet agent, attenuates the neurotoxicity induced by kainic acid in the rat. Life Sci. 1997;61(24):PL 373-81. DOI:10.1016/s0024-3205(97)00963-6 |
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