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ChemicalBook--->CAS DataBase List--->1452145-13-9

1452145-13-9

1452145-13-9 Structure

1452145-13-9 Structure
IdentificationBack Directory
[Name]

CCK2R Ligand-Linker Conjugates 1
[CAS]

1452145-13-9
[Synonyms]

CCK2R Ligand-Linker Conjugates 1
[Molecular Formula]

C72H110N12O27S
[MDL Number]

MFCD32263037
[MOL File]

1452145-13-9.mol
[Molecular Weight]

1607.77
Chemical PropertiesBack Directory
[Boiling point ]

1884.1±65.0 °C(Predicted)
[density ]

1.46±0.1 g/cm3(Predicted)
[pka]

2.93±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

CCK2R Ligand-Linker Conjugates 1 is a ligand-linker conjugate, which conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) via a hydrophilic peptide linker[1].
[References]

[1] Wayua C, et al. Selective Tumor Targeting of Desacetyl Vinblastine Hydrazide and Tubulysin B via Conjugation to a Cholecystokinin 2 Receptor (CCK2R) Ligand. Mol Pharm. 2015 Jul 6;12(7):2477-83. DOI:10.1021/acs.molpharmaceut.5b00218
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