| Identification | Back Directory | [Name]
.alpha.-Linolenic Acid-d5 | [CAS]
145191-04-4 | [Synonyms]
α-Linolenic Acid-d5
alfa-Linolenic Acid-d5
.alpha.-Linolenic Acid-d5
α-Linolenic Acid-d5 MaxSpec? Standard
9Z,12Z,15Z-octadecatrienoic-17,17’,18,18,18-d5acid | [Molecular Formula]
C18H30O2 | [MDL Number]
MFCD31814281 | [MOL File]
145191-04-4.mol | [Molecular Weight]
278.44 |
| Hazard Information | Back Directory | [Description]
α-Linolenic acid-d5 (ALA-d5) is intended for use as an internal standard for the quantification of ALA by GC- or LC-MS. α-Linolenic acid is an essential ω-3 polyunsaturated fatty acid found in plants.1 In vivo, it is converted to the longer-chain fatty acids eicosapentaenoic , docosapentaenoic , and docosahexaenoic acid .2 It is also catabolized via fatty acid β-oxidation for energy or the synthesis of saturated and monounsaturated fatty acids, or stored in adipose tissue. Dietary consumption of ALA-containing foods is positively associated with a moderately lower risk of cardiovascular disease.1
ALA-d5 MaxSpec? standard is a quantitative grade standard of ALA-d5 that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This ALA-d5 MaxSpec? standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. | [Uses]
α-Linolenic acid-d5 is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1]. | [References]
1. Pan, A., Chen, M., Chowdhury, R., et al. α-Linolenic acid and risk of cardiovascular disease: A systematic review and meta-analysis Am. J. Clin. Nutr. 96(6),1262-1273(2012).
2. Burdge, G.C. Metabolism of α-linolenic acid in humans Prostaglandins Leukot. Essent. Fatty Acids 75(3),161-168(2006). |
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