| Identification | Back Directory | [Name]
Pentanoic acid, 5-(dimethylamino)-, (6Z)-1,2-di-(4Z)-4-decen-1-yl-6-dodecen-1-yl ester | [CAS]
1450888-71-7 | [Synonyms]
CL1
Lipid CL1
Genevant CL1
LIPID CL1 (lipid 10)
(6Z,16Z)-12-((Z)-Dec-4-enyl)docosa-6,16-dien-11-yl 5-(dimethylamino)pentanoate
(6Z,16Z)-12-((Z)-dec-4-en-1-yl)docosa-6,16-dien-11-yl 5-(dimethylamino)pentanoate
Pentanoic acid, 5-(dimethylamino)-, (6Z)-1,2-di-(4Z)-4-decen-1-yl-6-dodecen-1-yl ester | [Molecular Formula]
C39H73NO2 | [MOL File]
1450888-71-7.mol | [Molecular Weight]
588 |
| Chemical Properties | Back Directory | [Boiling point ]
630.1±55.0 °C(Predicted) | [density ]
0.884±0.06 g/cm3(Predicted) | [form ]
Liquid | [pka]
9.62±0.28(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
Genevant CL1 (Lipid 10) is an ionizable lipid (pKa=6.3). Genevant CL1 can be used for mRNA lipid nanoparticle (LNP) vaccine delivery[1][2]. | [References]
[1] Lam K, Leung A, Martin A, et al. Unsaturated, Trialkyl Ionizable Lipids are Versatile Lipid-Nanoparticle Components for Therapeutic and Vaccine Applications. Adv Mater. 2023;35(15):e2209624. DOI:10.1002/adma.202209624
[2] Michael D Buschmann, et al. Nanomaterial Delivery Systems for mRNA Vaccines. Vaccines (Basel). 2021 Jan 19;9(1):65. DOI:10.3390/vaccines9010065 |
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InvivoChem
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13549236410 |
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https://www.invivochem.cn/ |
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