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ChemicalBook--->CAS DataBase List--->143853-58-1

143853-58-1

143853-58-1 Structure

143853-58-1 Structure
IdentificationBack Directory
[Name]

Protein E7(43-62)
[CAS]

143853-58-1
[Synonyms]

Protein E7(43-62)
[Molecular Formula]

C95H144N28O31S3
[MOL File]

143853-58-1.mol
[Molecular Weight]

2270.54
Chemical PropertiesBack Directory
[density ]

1.55±0.1 g/cm3(Predicted)
[Sequence]

Gly-Gln-Ala-Glu-Pro-Asp-Arg-Ala-His-Tyr-Asn-Ile-Val-Thr-Phe-Cys-Cys-Lys-Cys-Asp
Hazard InformationBack Directory
[Uses]

Protein E7(43-62) is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein)[1].
[in vivo]

Using an E7-derived peptide Protein E7(43-62), 50% of mice (C57BL/6 mice bearing human papilloma virus (HPV) E6/7 TC-1 tumors) are tumor free 60 days after treatment with Protein E7(43-62)-polymeric nanoparticle (PC7A NP)[1].

[References]

[1] Min Luo, et al. A STING-activating Nanovaccine for Cancer Immunotherapy. Nat Nanotechnol. 2017 Jul;12(7):648-654. DOI:10.1038/nnano.2017.52
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