午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

ChemicalBook--->CAS DataBase List--->143141-23-5

143141-23-5

143141-23-5 Structure

143141-23-5 Structure
IdentificationBack Directory
[Name]

1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-
[CAS]

143141-23-5
[Synonyms]

N-Benzenesulfonyl-7-azaindole
1-(Phenylsulfonyl)-7-azaindole
1-(Phenylsulphonyl)-7-azaindole
1-(Benzenesulfonyl)pyrrolo[2,3-b]pyridine
1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine
1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-
[Molecular Formula]

C13H10N2O2S
[MDL Number]

MFCD02083292
[MOL File]

143141-23-5.mol
[Molecular Weight]

258.3
Chemical PropertiesBack Directory
[Melting point ]

130-132 °C
[Boiling point ]

465.8±37.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[pka]

1.38±0.30(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H332-H335
[Precautionary statements ]

P261-P280-P305+P351+P338
[Hazard Codes ]

Xn
[Risk Statements ]

22
[HS Code ]

2933998090
Spectrum DetailBack Directory
[Spectrum Detail]

1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-(143141-23-5)1HNMR
Hazard InformationBack Directory
[Synthesis]

7-Azaindole

271-63-6

Benzenesulfonyl chloride

98-09-9

1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-

143141-23-5

4.2.4 Synthesis of 1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (5) In a dry and nitrogen purged round bottom flask, 1H-pyrrolo[2,3-b]pyridine (1.01 g, 8.58 mmol), tetrabutylammonium bromide (81 mg, 0.25 mmol), finely ground sodium hydroxide (1.02 g, 25.41 mmol) and dichloromethane (20 mL) were added. The mixture was cooled to 0 °C in an ice bath and stirred, followed by the slow dropwise addition of benzenesulfonyl chloride (1.35 mL, 10.59 mmol). The reaction mixture was gradually warmed to room temperature and stirred continuously at this temperature for 1 hour. Upon completion of the reaction, water (20 mL) was added for hydrolysis and then extracted twice with dichloromethane. The organic layers were combined, washed with saturated sodium chloride solution, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to give 2.38 g of a beige solid. The crude product was purified by silica gel column chromatography (eluent: cyclohexane/ethyl acetate=7:3) to give 2.17 g of white solid target product in 99% yield. 1H NMR (300 MHz, CDCl3) δ (ppm): 8.45 (dd, J = 1.5, 4.8 Hz, 1H), 8.20 (d, J = 7.5 Hz, 2H), 7.86 (dd, J = 1.5, 7.8 Hz, 1H), 7.73 (d, J = 4.0 Hz, 1H), 7.57 (dd, J = 7.4 Hz, 1H ), 7.52-7.47 (m, 2H), 7.19 (dd, J = 4.8, 7.8 Hz, 1H), 6.61 (d, J = 4.0 Hz, 1H). 13C NMR (75 MHz, CDCl3) δ (ppm): 144.7 (2C), 138.3, 134.1, 129.9, 129.1 (2C), 128.0 (2C), 126.5, 123.0, 119.0, 105.5.

[References]

[1] European Journal of Medicinal Chemistry, 2016, vol. 108, p. 701 - 719
[2] Patent: WO2016/114816, 2016, A1. Location in patent: Paragraph 0290
[3] Organic Letters, 2015, vol. 17, # 19, p. 4710 - 4713
[4] Tetrahedron, 1997, vol. 53, # 10, p. 3637 - 3648
[5] Patent: WO2006/50076, 2006, A1. Location in patent: Page/Page column 61
143141-23-5 suppliers list
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Website: www.yuhua99.com/ShowSupplierProductsList454175/0_EN.htm
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com
Company Name: Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel: +8613580539051 , +8613580539051
Website: www.yuhengpharm.com
Company Name: Hubei Ipure Biology Co., Ltd
Tel: +8613367258412 , +8613367258412
Website: www.ipurechemical.com
Company Name: Baoji Guokang Bio-Technology Co., Ltd.
Tel: 0917-3909592 13892490616 , 13892490616
Website: http://www.gk-bio.com
Company Name: Labnetwork lnc.
Tel: +86-27-50766799 +8618062016861 , +8618062016861
Website: www.labnetwork.com
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: +86-0551-65418684 +8618949823763 , +8618949823763
Website: www.tnjchem.com
Company Name: LEAPCHEM CO., LTD.
Tel: +86-852-30606658
Website: www.leapchem.com
Company Name: Suzhou ARTK Medchem Co., Ltd.
Tel: +86-512-68323658 +86-18168183658 , +86-18168183658
Website:
Company Name: DAYANG CHEM (HANGZHOU) CO.,LTD
Tel: +86-88938639 +86-17705817739 , +86-17705817739
Website: www.dycnchem.com
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-6139-8061 +86-86-13650506873 , +86-86-13650506873
Website: http://www.chemdad.com/
Company Name: Amadis Chemical Company Limited
Tel: 571-89925085
Website: http://www.amadischem.com
Company Name: Pure Chemistry Scientific Inc.  
Tel: 001-857-928-2050 or 1-888-588-9418
Website: www.chemreagents.com
Company Name: Nanjing Chemlin Chemical Co., Ltd  
Tel: 025-83697070
Website: www.echemlin.cn
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Tel: 021-54306202 13764082696
Website: https://www.hanhongsci.com
Company Name: SpringPharma Tech Co.,Ltd  
Tel: +86-25-68710855, +86-25-68710897
Website: www.springpharma.net
Company Name: Shanghai Sunway Pharmaceutical Technology Co., Ltd  
Tel: 18270980682
Website: www.sunwaypharm.cn
Company Name: NovoChemy Ltd.  
Tel: 021-31261262/ 49 (0)17662837245
Website: www.novochemy.com
Tags:143141-23-5 Related Product Information
271-63-6

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.