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ChemicalBook--->CAS DataBase List--->142986-44-5

142986-44-5

142986-44-5 Structure

142986-44-5 Structure
IdentificationBack Directory
[Name]

STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1
[CAS]

142986-44-5
[Synonyms]

PAMAMG1.0
pamam dendrimer, generation 1 solution
STARBURST(R) (PAMAM) DENDRIMER, GENERATION 1
4,7,11,14,18,21-Hexaazatetracosanediamide, 95%
PAMAM dendrimer, ethylenediamine core, generation 1.0 solution
STARBURST (PAMAM) DENDRIMER, GENERATION 1, 20 WT. % SOLUTION IN METHYL ALCOHOL
PAMAM dendrimer, ethylenediamine core, generation 1.0 solution 20 wt. % in methanol
4,7,11,14,18,21-Hexaazatetracosanediamide, N1,N24-bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-
[Molecular Formula]

C62H128N26O12
[MDL Number]

MFCD00192448
[MOL File]

142986-44-5.mol
[Molecular Weight]

1429.85
Chemical PropertiesBack Directory
[Boiling point ]

64.7 °C
[density ]

0.82 g/mL at 25 °C
[refractive index ]

n20/D 1.362
[Fp ]

52 °F
[storage temp. ]

2-8°C
[form ]

20 wt.% in methanol
[color ]

Colorless to light yellow
[InChIKey]

QVWIZHOFYGKROL-UHFFFAOYSA-N
[SMILES]

C(NCCN)(=O)CCN(CCC(NCCN)=O)CCNC(=O)CCN(CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCN(CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCC(=O)NCCN(CCC(NCCN)=O)CCC(NCCN)=O
Safety DataBack Directory
[Hazard Codes ]

F,T
[Risk Statements ]

11-23/24/25-39/23/24/25-36/37/38
[Safety Statements ]

7-16-23-45-36/37-26
[RIDADR ]

UN 1230 3/PG 2
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Starburst 1st Generation (PAMAM G1.0) is a Polyamidoamine (HY-164657; PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vitro. Starburst 1st Generation conjugated to di-n-dodecylamine and encapsulating 5-Fluorouracil (HY-90006) increase the solubility of 5-Fluorouracil and are cytotoxic to AGS gastric adenocarcinoma cells[1].
[References]

[1] Ender Sarigul, et al. Polyamidoamine Dendron-Bearing Lipids as Drug-Delivery Excipients. Molecules. 2022 Nov 13;27(22):7817. DOI:10.3390/molecules27227817
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