| Identification | Back Directory | [Name]
Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]- | [CAS]
1429028-96-5 | [Synonyms]
4,9-Bis3-(4-methyl-1-piperazinyl)propylamino-2,7-bis3-(4-morpholinyl)propylbenzolmn3,8phenanthroline-1,3,6,8(2H,7H)-tetrone
Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]- | [Molecular Formula]
C44H66N10O6 | [MOL File]
1429028-96-5.mol | [Molecular Weight]
831.06 |
| Chemical Properties | Back Directory | [Boiling point ]
945.3±65.0 °C(Predicted) | [density ]
1.256±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 33.33 mg/mL (40.11 mM; ultrasonic and adjust pH to 8 with HCl) | [form ]
Solid | [pka]
7.96±0.10(Predicted) | [color ]
Blue to purple |
| Hazard Information | Back Directory | [Uses]
MM41 is a potent stabilizer of human telomeric and gene promoter DNA quadruplexes. MM41 is potently against the MIA PaCa-2 pancreatic cancer cell line with IC50 value of <10 nM[1]. | [Biological Activity]
MM41 is a potent stabilizer of human telomeric and gene promoter DNA quadruplexes. MM41 is potently against the MIA PaCa-2 pancreatic cancer cell line with IC50 value of <10 nM[1]. | [References]
[1]. Marialuisa Micco, et al. Structure-based design and evaluation of naphthalene diimide G-quadruplex ligands as telomere targeting agents in pancreatic cancer cells. J Med Chem |
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