Identification | Back Directory | [Name]
(Z)-4-(5-((5-(4-bromophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid | [CAS]
1427538-26-8 | [Synonyms]
ASK1-IN-4 3-Thiazolidinebutanoic acid, 5-[[5-(4-bromophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-, (5Z)- (Z)-4-(5-((5-(4-bromophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid 4-((5Z)-5-{[5-(4-bromophenyl)-2-furyl]methylene}-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)butanoic acid | [Molecular Formula]
C18H14BrNO4S2 | [MOL File]
1427538-26-8.mol | [Molecular Weight]
452.34 |
Hazard Information | Back Directory | [Uses]
ASK1-IN-4 (Compound 17) is an ASK1 inhibitor (IC50=0.2 μM). ASK1-IN-4 interacts with ATP-binding site of ASK1[1]. | [IC 50]
ASK1: .2 μM (IC50) | [References]
[1] Starosyla SA,et al. ASK1 pharmacophore model derived from diverse classes of inhibitors. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4418-4423. DOI:10.1016/j.bmcl.2014.08.011 |
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Company Name: |
OTAVA chemicals
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Tel: |
416 305 9979 (Canada) |
Website: |
www.otavachemicals.com |
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