午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

ChemicalBook--->CAS DataBase List--->141676-35-9

141676-35-9

141676-35-9 Structure

141676-35-9 Structure
IdentificationBack Directory
[Name]

Vasonatrin Peptide (VNP)
[CAS]

141676-35-9
[Synonyms]

Vasonatrin Peptide (VNP)
H-Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH
GLY-LEU-SER-LYS-GLY-CYS-PHE-GLY-LEU-LYS-LEU-ASP-ARG-ILE-GLY-SER-MET-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR ((DISULFIDE BRIDGE: CYS6-CYS22)
[Molecular Formula]

C124H198N36O36S3
[MDL Number]

MFCD00671451
[MOL File]

141676-35-9.mol
[Molecular Weight]

2865.34
Chemical PropertiesBack Directory
[density ]

1.47±0.1 g/cm3(Predicted)
[Sequence]

Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfide bridge: Cys6-Cys22)
Hazard InformationBack Directory
[Uses]

Vasonatrin Peptide (VNP) is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). Vasonatrin peptide possesses the venodilating actions of CNP, the natriuretic actions of ANP, and unique arterial vasodilating actions not associated with either ANP or CNP. Vasonatrin Peptide protects the diabetic heart against ischemia-reperfusion injury by inhibiting ER stress via the cGMP-PKG signaling pathway[1][2][3].
[in vivo]

Vasonatrin peptide (100 μg/kg; i.v. ; 10 min before reperfusion) attenuates myocardial ischemia-reperfusion injury in diabetic rats[3].

Animal Model:High-fat diet-fed streptozotocin-induced diabetic Sprague-Dawley rats[3]
Dosage:100 μg/kg
Administration:I.v. ; 10 min before reperfusion
Result:Significantly improved the instantaneous first derivation of left ventricle pressure (±LV dP/dtmax) and LV systolic pressure and reduced LV end-diastolic pressure, apoptosis index, caspase-3 activity, plasma creatine kinase (CK), and lactate dehydrogenase (LDH) activities. Inhibited endoplasmic reticulum (ER) stress by suppressing glucose-regulated protein 78 (GRP78) and C/EBP homologous protein (CHOP).
[References]

[1] Wei CM, et al. Vasonatrin peptide: a unique synthetic natriuretic and vasorelaxing peptide. J Clin Invest. 1993;92(4):2048-2052. DOI:10.1172/JCI116800
[2] Chen BY, et al. Vasonatrin peptide, a new regulator of adiponectin and interleukin-6 production in adipocytes. J Endocrinol Invest. 2011;34(10):742-746. DOI:10.3275/7727
[3] Shi Z, et al. Vasonatrin peptide attenuates myocardial ischemia-reperfusion injury in diabetic rats and underlying mechanisms. Am J Physiol Heart Circ Physiol. 2015;308(4):H281-H290. DOI:10.1152/ajpheart.00666.2014
141676-35-9 suppliers list
Company Name: Shenzhen Nexconn Pharmatechs Ltd
Tel: +86-755-89396905 +86-15013857715 , +86-15013857715
Website: www.yuhua99.com/ShowSupplierProductsList31188/0_EN.htm
Company Name: BOC Sciences
Tel: +1-631-485-4226
Website: www.bocsci.com/
Company Name: Cellmano Biotech Limited
Tel: 0551-65326643 18156095617 , 18156095617
Website: http://www.cellmano.com/
Company Name: Hangzhou Go Top Peptide Biotech
Tel: 0571-88211921
Website: http://www.gotopbio.com/
Company Name: Nanjing TGpeptide
Tel: +86-13347807150
Website: tgpeptides.com/index.aspx
Company Name: Changsha MOL Changes Biotechnology Co., Ltd.
Tel: +8619375158599 , +8619375158599
Website: www.molchanges.com
Company Name: GL Biochem (Shanghai) Ltd  
Tel: 21-61263452 13641803416
Website: http://www.glschina.com/
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Tel: 021-54306202 13764082696
Website: https://www.hanhongsci.com
Company Name: Chemsky (shanghai) International Co.,Ltd  
Tel: 021-50135380
Website: www.shchemsky.com
Company Name: Cellmano Biotech Limited  
Tel: 0551-65326643 18156095617
Website: https://www.cellmano.com
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Website: https://www.bocsci.com
Company Name: Creative Peptides   
Tel:
Website: www.creative-peptides.com
Company Name: Nanjing Peptide Biotech Ltd.  
Tel: 025-58361106-805 15951641583
Website: www.njpeptide.com
Company Name: Chengdu Youngshe Chemical Co., Ltd.  
Tel: +86-17380623303
Website: https://shop326109856.taobao.com/
Company Name: Hangzhou Peptidego Biotech Co.,Ltd.  
Tel: 0571-87213919
Website: http://www.peptidego.com
Company Name: Shanghai Han-Xiang Chemical Co., Ltd.  
Tel: 15971444841
Website: www.biochempartner.com.cn
Company Name: Nanjing Meihao Pharmaceutical Technology Co., Ltd.  
Tel: meitaochem@126.com
Website: www.yuhua99.com/ShowSupplierProductsList31244/0_EN.htm
Company Name: Nanjing TGpeptide Biotechnology Co.,Ltd.  
Tel: 18115476705
Website: http://www.tgpeptide.com/Index.aspx
Tags:141676-35-9 Related Product Information
11000-17-2 849479-74-9 1356383-11-3 113-80-4 37221-79-7 9034-50-8 74927-14-3 172486-63-4

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.