| Identification | Back Directory | [Name]
Propanoic acid, 2-[3-[[5-[[[(1S)-1-[4-(1,1-dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]phenoxy]-2-methyl- | [CAS]
1415321-54-8 | [Synonyms]
Propanoic acid, 2-[3-[[5-[[[(1S)-1-[4-(1,1-dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]phenoxy]-2-methyl- | [Molecular Formula]
C34H40N2O4 | [MOL File]
1415321-54-8.mol | [Molecular Weight]
540.69 |
| Hazard Information | Back Directory | [Uses]
Anticancer agent 183 (example 48) is a non-agonistic PPARG modulator. Anticancer agent 183 has a high affinity to PPARG (PPARγ). Anticancer agent 183 inhibits kinase-mediated phosphorylation of PPARG. Anticancer agent 183 can used for research on metabolic diseases to avoid side effects[1]. | [IC 50]
PPAR-γ | [References]
[1] Theodore Mark Kamenecka, et al. N-benzylindole modulators of pparg. 2012. |
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