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ChemicalBook--->CAS DataBase List--->137254-39-8

137254-39-8

137254-39-8 Structure

137254-39-8 Structure
IdentificationBack Directory
[Name]

1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC
[CAS]

137254-39-8
[Synonyms]

AUN-54398
1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC
[Molecular Formula]

C48H88NO8P
[MOL File]

137254-39-8.mol
[Molecular Weight]

838.2
Chemical PropertiesBack Directory
[solubility ]

Chloroform:10.0(Max Conc. mg/mL);11.93(Max Conc. mM)
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS06,GHS07,GHS08,GHS09
[Signal word ]

Danger
Hazard InformationBack Directory
[Description]

AUN-54398 is a phospholipid that contains stearic acid and adrenic acid at the sn-1 and sn-2 positions, respectively. This product has no formal name.
[Uses]

1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC (PC(18:0/22:4)) is an inhibitor of cyclin-dependent kinases (CDKs).? 1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC induces apoptosis and inhibits the growth of various cancer cell lines[1].
[Definition]

ChEBI: 1-octadecanoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphocholine is a phosphatidylcholine 40:4 in which the two acyl substituents at positions 1 and 2 are specified as stearoyl and (7Z,10Z,13Z,16Z)-docosatetraenoyl respectively. It has a role as a mouse metabolite. It is functionally related to an octadecanoic acid and an all-cis-docosa-7,10,13,16-tetraenoic acid.
[References]

[1] Bell, M. V., et al. Molecular Species Composition of the Major Diacyl Glycerophospholipids from Muscle, Liver, Retina and Brain of Cod (Gadus morhua).? Lipids, 26(8), 565–573.
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