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ChemicalBook--->CAS DataBase List--->136132-68-8

136132-68-8

136132-68-8 Structure

136132-68-8 Structure
IdentificationBack Directory
[Name]

MBP 4-14
[CAS]

136132-68-8
[Synonyms]

MBP 4-14
PYR-KRPSQRSKYL
PGLU-KRPSQRSKYL
[PYR4]-MBP (4-14)
PKC substrate (MBP)
PKC SELECTIVE SUBSTRATE
[PYR4]-MBP (4-14) (BOVINE)
[PGLU4]-MYELIN BASIC PROTEIN 4-14
[PGLU4]-(4-14) MYELIN BASIC PROTEIN
PROTEIN KINASE C SELECTIVE SUBSTRATE
PROTEIN KINASE C SUBSTRATE, MBP 4-14
[pglu4]-myelin basic protein fragment 4-14
GLP-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU
PYR-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU
[PYR4]-MYELIN BASIC PROTEIN (4-14) (BOVINE)
PGLU-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU
PYR-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU-OH
PGLU-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU-OH
GLP-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU: GLP-KRPSQRSKYL
PROTEIN KINASE C SELECTIVE SUBSTRATE >96 % SYNTHETIC (MYELIN BA
L-Leucine, 5-oxo-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-lysyl-L-tyrosyl- (9CI)
[Molecular Formula]

C60H100N20O17
[MDL Number]

MFCD00133754
[MOL File]

136132-68-8.mol
[Molecular Weight]

1373.56
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[form ]

Solid
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

[pGlu4]-Myelin Basic Protein (4-14) is the phosphorylated 4-14 fragment (EKRPSQRSKYL) of myelin basic protein (MBP)[1]. [pGlu4]-Myelin Basic Protein (4-14) surrounds the serine residue in position 8 of the myelin basic protein[2].
[References]

[1] Durocher Y, et al. Activation of an 85 kDa ribosomal S6 kinase during serotonin-induced oocyte maturation. Int J Dev Biol. 1996 Jun;40(3):557-66. PMID:8840188
[2] Loog M, et al. Comparison of Substrate Specificities of Protein Kinases A and C Based on Peptide Substrates[J]. Bioorganic Chemistry, 1994, 22(3): 328-336.
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