| Identification | Back Directory | [Name]
DNP-PEG2-acid | [CAS]
1353011-89-8 | [Synonyms]
DNP-PEG-COOH
DNP-PEG2-acid
DNP-PEG2-COOH
DNP-NH-PEG2-C2-acid
Propanoic acid, 3-[2-[2-[(2,4-dinitrophenyl)amino]ethoxy]ethoxy]- | [Molecular Formula]
C13H17N3O8 | [MDL Number]
MFCD20926369 | [MOL File]
1353011-89-8.mol | [Molecular Weight]
343.29 |
| Chemical Properties | Back Directory | [Boiling point ]
573.7±50.0 °C(Predicted) | [density ]
1.436±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.28±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
DNP-PEG2-acid is a PEG linker containing a DNP and carboxylic acid moiety. DNP is involved in biological applications such as participating in ion transport across membranes. The terminal carboxylic acid can react with primary amines in the presence of EDC and HATU to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. | [Uses]
DNP-NH-PEG2-C2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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