Hazard Information | Back Directory | [Description]
Fmoc-Lys (biotin-PEG4)-OH is a Lysine embedded biotin PEG linkers containing a carboxylic group and Fmoc-protected amine. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible amide bonds. The Fmoc group can be deprotected under basic condition to release the free amine which can be used for further conjugations. | [Uses]
Fmoc-Lys (biotin-PEG4)-OH is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329 |
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Company Name: |
Enzo Biochem Inc
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Tel: |
Enzo Biochem Inc. 13797054060 |
Website: |
www.enzo.com |
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