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ChemicalBook--->CAS DataBase List--->1315378-75-6

1315378-75-6

1315378-75-6 Structure

1315378-75-6 Structure
IdentificationBack Directory
[Name]

(2S,3S,4S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineaceticacid4-methoxy-7-nitro-1H-indolinylamide
[CAS]

1315378-75-6
[Synonyms]

MNI caged kainic acid
(2S,3S,4S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineaceticacid4-methoxy-7-nitro-1H-indolinylamide
(3S,4S)3-[2-(2,3-Dihydro-4-methoxy-7-nitro-1H-indol-1-yl)-2-oxoethyl]-4-(1-methylethenyl)-L-proline
L-Proline, 3-[2-(2,3-dihydro-4-methoxy-7-nitro-1H-indol-1-yl)-2-oxoethyl]-4-(1-methylethenyl)-, (3S,4S)-
[Molecular Formula]

C19H23N3O6
[MDL Number]

MFCD18086846
[MOL File]

1315378-75-6.mol
[Molecular Weight]

389.4
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
Hazard InformationBack Directory
[Uses]

MNI-caged kainate is a photoprotected neuroactive amino acid with the activity to generate large inward currents. MNI-caged kainate can be released at the resting membrane potential of Purkinje cells and generate significant inward currents. The release of MNI-caged kainate results in approximately 40% of the current being generated through AMPA receptor activation. MNI-caged kainate is used to study fast synaptic receptor mechanisms. The photorelease time of MNI-caged kainate is in the sub-microsecond range, making it suitable for investigating the mechanisms of fast synaptic transmission[1].
[References]

[1] New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups
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