Identification | Back Directory | [Name]
(2S,3S,4S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineaceticacid4-methoxy-7-nitro-1H-indolinylamide | [CAS]
1315378-75-6 | [Synonyms]
MNI caged kainic acid (2S,3S,4S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineaceticacid4-methoxy-7-nitro-1H-indolinylamide (3S,4S)3-[2-(2,3-Dihydro-4-methoxy-7-nitro-1H-indol-1-yl)-2-oxoethyl]-4-(1-methylethenyl)-L-proline L-Proline, 3-[2-(2,3-dihydro-4-methoxy-7-nitro-1H-indol-1-yl)-2-oxoethyl]-4-(1-methylethenyl)-, (3S,4S)- | [Molecular Formula]
C19H23N3O6 | [MDL Number]
MFCD18086846 | [MOL File]
1315378-75-6.mol | [Molecular Weight]
389.4 |
Hazard Information | Back Directory | [Uses]
MNI-caged kainate is a photoprotected neuroactive amino acid with the activity to generate large inward currents. MNI-caged kainate can be released at the resting membrane potential of Purkinje cells and generate significant inward currents. The release of MNI-caged kainate results in approximately 40% of the current being generated through AMPA receptor activation. MNI-caged kainate is used to study fast synaptic receptor mechanisms. The photorelease time of MNI-caged kainate is in the sub-microsecond range, making it suitable for investigating the mechanisms of fast synaptic transmission[1]. | [References]
[1] New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups |
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Energy Chemical
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http://www.energy-chemical.com |
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