Identification | Back Directory | [Name]
5-O-TERT-BUTYLDIPHENYLSILYL-2,3-O-ISOPROPYLIDENE-D-LYXONO-1,4-LACTONE | [CAS]
130222-84-3 | [Synonyms]
5-O-t-Butyldiphenyl silyl-2,3-O-isopropylidene-D-ribono-1,4-lactone 5-O-TERT-BUTYLDIPHENYLSILYL-2,3-O-ISOPROPYLIDENE-D-LYXONO-1,4-LACTONE D-Ribonic acid, 5-O-[(1,1-dimethylethyl)diphenylsilyl]-2,3-O-(1-methylethylidene)-, γ-lactone (3AR,6R,6AR)-6-(((TERT-BUTYLDIPHENYLSILYL)OXY)METHYL)-2,2-DIMETHYLDIHYDROFURO[3,4-D][1,3]DIOXOL-4(3AH)-ONE | [Molecular Formula]
C24H30O5Si | [MDL Number]
MFCD01075715 | [MOL File]
130222-84-3.mol | [Molecular Weight]
426.578 |
Hazard Information | Back Directory | [Uses]
5-O-(tert-Butyldiphenylsilyl)-2,3-isopropylidene-D-ribonolactone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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