Identification | Back Directory | [Name]
3-azidotyrosine | [CAS]
129960-90-3 | [Synonyms]
3-azidotyrosine H-L-Tyr(3-N3)-OH 3-azido-L-tyrosine (2S)-2-Amino-3-(3-azido-4-hydroxyphenyl)propanoic acid | [Molecular Formula]
C9H10N4O3 | [MDL Number]
MFCD19105590 | [MOL File]
129960-90-3.mol | [Molecular Weight]
222.2 |
Hazard Information | Back Directory | [Uses]
H-L-Tyr(3-N3)-OH is a click chemistry reagent containing an azide[1]. H-L-Tyr(3-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [References]
[1] Yokogawa T, et al. Incorporation of 3-azidotyrosine into proteins through engineering yeast tyrosyl-tRNA synthetase and its application to site-selective protein modification. Methods Mol Biol. 2010;607:227-42. DOI:10.1007/978-1-60327-331-2_19 |
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