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ChemicalBook--->CAS DataBase List--->1287761-01-6

1287761-01-6

1287761-01-6 Structure

1287761-01-6 Structure
IdentificationBack Directory
[Name]

PTUPB
[CAS]

1287761-01-6
[Synonyms]

PTUPB
4-(5-Phenyl-3-[3-[3-(4-trifluoromethyl-phenyl)-ureido]-propyl]-pyrazol-1-yl)benzenesulfonamide
4-(5-Phenyl-3-(3-(3-(4-(trifluoromethyl)phenyl)ureido)propyl)-1H-pyrazol-1-yl)benzenesulfonamide
Benzenesulfonamide, 4-[5-phenyl-3-[3-[[[[4-(trifluoromethyl)phenyl]amino]carbonyl]amino]propyl]-1H-pyrazol-1-yl]-
Cyclooxygenase,inhibit,Non-alcoholic,COX,obesity,Metastasis,liver,fatty,steatosis,HUVECs,HFD,hepatic,Inhibitor,PTUPB,LLC,disease
[Molecular Formula]

C26H24F3N5O3S
[MDL Number]

MFCD32701914
[MOL File]

1287761-01-6.mol
[Molecular Weight]

543.56
Chemical PropertiesBack Directory
[solubility ]

DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.30 mg/ml; Ethanol: 1 mg/ml
[form ]

A solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

4-(5-Phenyl-3-[3-[3-(4-trifluoromethyl-phenyl)-ureido]-propyl]-pyrazol-1-yl) benzenesulfonamide is used as a PTUPB; COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence.
Spectrum DetailBack Directory
[Spectrum Detail]

PTUPB(1287761-01-6)1HNMR
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