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        ChemicalBook--->CAS DataBase List--->12777-70-7

        12777-70-7

        12777-70-7 Structure

        12777-70-7 Structure
        IdentificationBack Directory
        [Name]

        dryocrassin
        [CAS]

        12777-70-7
        [Synonyms]

        dryocrassin
        Dryocrassin ABBA)
        Tetraalbaspidin ABBA
        Methylenebisnorflavaspidic acid ABBA
        2,5-Cyclohexadien-1-one, 2,2'-[methylenebis[[2,4,6-trihydroxy-5-(1-oxobutyl)-3,1-phenylene]methylene]]bis[6-acetyl-3,5-dihydroxy-4,4-dimethyl- (9CI)
        2-acetyl-4-[[3-[[3-[(5-acetyl-2,6-dihydroxy-3,3-dimethyl-4-oxocyclohexa-1,5-dien-1-yl)methyl]-5-butanoyl-2,4,6-trihydroxyphenyl]methyl]-5-butanoyl-2,4,6-trihydroxyphenyl]methyl]-3,5-dihydroxy-6,6-dimethylcyclohexa-2,4-dien-1-one
        [Molecular Formula]

        C45H48O16
        [MDL Number]

        MFCD20527289
        [MOL File]

        12777-70-7.mol
        [Molecular Weight]

        820.83
        Chemical PropertiesBack Directory
        [Boiling point ]

        1089.0±65.0 °C(Predicted)
        [density ]

        1.474±0.06 g/cm3 (20 ºC 760 Torr)
        [solubility ]

        Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
        [form ]

        powder
        [pka]

        4.20±1.00(Predicted)
        [color ]

        Yellow
        Safety DataBack Directory
        [Symbol(GHS) ]


        GHS07
        [Signal word ]

        Warning
        [Hazard statements ]

        H315-H319
        [Precautionary statements ]

        P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
        Questions And Answer(Q&A)Back Directory
        [Biological Activity]

        Dryocrassin is a flavonoid natural product, a phloroglucinol derivative derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities. Biological and pharmacological activities of dryocrassin have attracted attention. Dryocrassin exhibits antiviral activity against H5N1 avian influenza virus. Dryocrassin inhibits the coagulase activity of Staphylococcus aureus vWbp. Dryocrassin suppresses immunostimulatory function of dendritic cells and prolongs skin allograft survival.
        Hazard InformationBack Directory
        [target]

        Influenza virus | p53 | Bcl-2/Bax | Caspase | IL Receptor | TNF-α
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