Identification | Back Directory | [Name]
H-GLY-PEN-GLY-ARG-GLY-ASP-SER-PRO-CYS-ALA-OH | [CAS]
126716-28-7 | [Synonyms]
H-GLY-PEN-GLY-ARG-GLY-ASP-SER-PRO-CYS-ALA-OH H-Gly-Pen-Gly-Arg-Gly-Asp-Ser-Pro-Cys-Ala-OH, (Disulfide bond between Pen2 and Cys9) H-Gly-Pen-Gly-Arg-Gly-Asp-Ser-Pro-Cys-Ala-OH (Disulfide bond between Pen2 and Cys?) Pyrrolo[2,1-g][1,2,5,8,11,14,17,20,23]dithiaheptaazacyclohexacosine,cyclic peptide deriv H-Gly-Pen-Gly-Arg-Gly-Asp-Ser-Pro-Cys-Ala-OH trifluoroacetate salt (Disulfide bond between Pen2 and Cys) H-Gly-Pen-Gly-Arg-Gly-Asp-Ser-Pro-Cys-Ala-OH trifluoroacetate salt (Disulfide bond between Pen? and Cys?) L-Alanine, glycyl-3-mercapto-L-valylglycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-cysteinyl-, cyclic (2→9)-disulfide | [Molecular Formula]
C35H57N13O14S2 | [MDL Number]
MFCD00886860 | [MOL File]
126716-28-7.mol | [Molecular Weight]
948.04 |
Hazard Information | Back Directory | [Uses]
G-Pen-GRGDSPCA is an αvβ3-inhibiting RGD peptide. G-Pen-GRGDSPCA can limit neointimal hyperplasia and lumen stenosis after vascular injury, as well as regulate the migration and proliferation of smooth muscle cells. G-Pen-GRGDSPCA can be used in the study of the mechanism of vascular injury repair[1]. | [References]
[1] Wei-Jun Cai, et al. Activation of the integrins alpha 5beta 1 and alpha v beta 3 and focal adhesion kinase (FAK) during arteriogenesis. Mol Cell Biochem. 2009 Feb;322(1-2):161-9. DOI:10.1007/s11010-008-9953-8 |
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