| Identification | Back Directory | [Name]
85548e | [CAS]
124020-62-8 | [Synonyms]
85548e
U85548e
U-85548e
U 85548e
L-Valine, L-valyl-L-seryl-L-glutaminyl-L-asparaginyl-(2S,4S,5S)-5-amino-4-hydroxy-7-methyl-2-(1-methylethyl)octanoyl-L-isoleucyl- | [Molecular Formula]
C40H73N9O12 | [MOL File]
124020-62-8.mol | [Molecular Weight]
872.08 |
| Hazard Information | Back Directory | [Uses]
U-85548E is an HIV protease inhibitor with nanomolar affinity for HIV-1 aspartic protease. By studying its structure-activity relationship, a potent nanomolar inhibitor with inhibitory effects on both HIV-1 and HIV-2 proteases was designed, and its binding mode was studied by X-ray crystallography and molecular modeling. | [References]
[1] HIV protease (HIV PR) inhibitor structure‐activity‐selectivity, and active site molecular modeling of high affinity Leu [CH(OH)CH2]Val modified viral and nonviral?… |
|
| Company Name: |
CHEMICAL LAND21
|
| Tel: |
82- 2 -783 - 8063 |
| Website: |
www.chemicalland21.com |
|