| Identification | Back Directory | [Name]
3-FLUORO-4-METHOXYBENZYLAMINE | [CAS]
123652-95-9 | [Synonyms]
RARECHEM AL BW 0863
(3-Fluoro-4-methoxyphenyl)
3-Fluoro-4-methoxybenzylamin
3-FLUORO-4-METHOXYBENZYLAMINE
3-fluoro-4-methoxybenzylaminie
2-Fluoro-4-(aminomethyl)anisole
3-Fluoro-4-methoxybenzylamine,97%
BenzeneMethanaMine, 3-fluoro-4-Methoxy-
1-(3-fluoro-4-methoxyphenyl)methanamine
Benzenemethanamine, 3-fluoro-4-methoxy- (9CI) | [Molecular Formula]
C8H10FNO | [MDL Number]
MFCD04116360 | [MOL File]
123652-95-9.mol | [Molecular Weight]
155.17 |
| Chemical Properties | Back Directory | [Boiling point ]
234.9±25.0 °C(Predicted) | [density ]
1.127±0.06 g/cm3(Predicted) | [refractive index ]
1.5280 | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [pka]
9.04±0.10(Predicted) | [Appearance]
Colorless to light yellow Liquid | [Water Solubility ]
Immiscible with water. | [Sensitive ]
Air Sensitive |
| Hazard Information | Back Directory | [Uses]
3-Fluoro-4-methoxybenzylamine is used as an intermediate in organic synthesis. | [Synthesis]
Example 2.1.1: Preparation of (3-fluoro-4-methoxyphenyl) methylamine (ICb). To a solution of 3-fluoro-4-methoxybenzyl cyanide (ICa, 68.0 g, 450 mmol, 1 equiv) in methanol (2 L) was added Raney nickel (Raney-Ni, 70.0 g). After addition, the reaction mixture was stirred at room temperature overnight. After completion of the reaction, the solid formed was removed by filtration and the solid was washed with methanol. The clarified filtrate was concentrated under reduced pressure to afford the title compound (3-fluoro-4-methoxyphenyl)methylamine (ICb, 62.8 g, 90% yield) as a yellow oil. | [References]
[1] Patent: WO2015/127137, 2015, A1. Location in patent: Page/Page column 148 |
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