| Identification | Back Directory | [Name]
Indacaterol IMrity | [CAS]
1235445-80-3 | [Synonyms]
Indacaterol IMP
(S)-Indacaterol
Indacaterol IMrity
Indoterol impurity 06
(S)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
2(1H)-Quinolinone, 5-[(1S)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy- | [Molecular Formula]
C24H28N2O3 | [MDL Number]
MFCD28988800 | [MOL File]
1235445-80-3.mol | [Molecular Weight]
392.49 |
| Hazard Information | Back Directory | [Uses]
(S)-Indacaterol is the S-enantiomer of Indacaterol (HY-14299). Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist[1][2]. | [References]
[1] Jadwiga A Wedzicha, et al. Indacaterol-Glycopyrronium versus Salmeterol-Fluticasone for COPD. N Engl J Med. 2016 Jun 9;374(23):2222-34. DOI:10.1056/NEJMoa1516385
[2] Lee SU, et al. Indacaterol inhibits tumor cell invasiveness and MMP-9 expression by suppressing IKK/NF-κB activation. Mol Cells. 2014 Aug;37(8):585-91. DOI:10.14348/molcells.2014.0076 |
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