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ChemicalBook--->CAS DataBase List--->1233355-57-1

1233355-57-1

1233355-57-1 Structure

1233355-57-1 Structure
IdentificationBack Directory
[Name]

LDN 209929 dihydrochloride
[CAS]

1233355-57-1
[Synonyms]

LDN 209929 dihydrochloride
1-Propanamine, 3-[(2-chloro-7-methoxy-9-acridinyl)thio]-
[Molecular Formula]

C17H17ClN2OS
[MOL File]

1233355-57-1.mol
[Molecular Weight]

332.85
Hazard InformationBack Directory
[Uses]

LDN-209929 is a potent haspin kinase inhibitor, with IC50 values of 55 nM and 9.9 μM for Haspin and DYRK2, respectively[1].
[References]

[1] Gregory D Cuny, et al. Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3491-4. PMID:20836251
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