Identification | Back Directory | [Name]
LDN 209929 dihydrochloride | [CAS]
1233355-57-1 | [Synonyms]
LDN 209929 dihydrochloride 1-Propanamine, 3-[(2-chloro-7-methoxy-9-acridinyl)thio]- | [Molecular Formula]
C17H17ClN2OS | [MOL File]
1233355-57-1.mol | [Molecular Weight]
332.85 |
Hazard Information | Back Directory | [Uses]
LDN-209929 is a potent haspin kinase inhibitor, with IC50 values of 55 nM and 9.9 μM for Haspin and DYRK2, respectively[1]. | [References]
[1] Gregory D Cuny, et al. Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3491-4. PMID:20836251 |
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