Identification | Back Directory | [Name]
(diethyl)[3-phenyl-1,2,4-oxadiazole-5-ethyl]ammonium chloride | [CAS]
1219-20-1 | [Synonyms]
Oxolamine HCl 683 M hydrochloride AF 438 hydrochloride Oxolamine hydrochloride (diethyl)[3-phenyl-1,2,4-oxadiazole-5-ethyl]ammonium chloride | [EINECS(EC#)]
214-940-6 | [Molecular Formula]
C14H20ClN3O | [MOL File]
1219-20-1.mol | [Molecular Weight]
281.781 |
Hazard Information | Back Directory | [Uses]
Oxolamine (SKF-9976) hydrochloride is an orally active cough suppressant that can be used for the research of respiratory tract diseases. Oxolamine hydrochloride also exhibits anti-inflammatory effect[1][2]. | [Safety Profile]
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx and HCl. | [References]
[1] Kirilmaz L, et, al. Sustained-release dosage form of oxolamine citrate: preparation and release kinetics. J Microencapsul. Apr-Jun 1992;9(2):167-72. DOI:10.3109/02652049109021232 [2] GIUDICI G, et, al. [On the anti-inflammatory action of oxolamine citrate]. Minerva Med. 1961 Oct 31;52:3752-5. PMID:13898986 |
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