| Identification | Back Directory | [Name]
JMV 167 | [CAS]
120775-49-7 | [Synonyms]
JMV 167
Boc-O-Sulfo-L-Tyr-L-Nle-Gly-D-Trp-L-Nle-L-Asp-(2-phenylethyl)NH2
L-α-Asparagine, N2-[N-[N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-O-sulfo-L-tyrosyl]-L-norleucyl]glycyl]-D-tryptophyl]-L-norleucyl]-N-(2-phenylethyl)- (9CI) | [Molecular Formula]
C51H68N8O14S | [MOL File]
120775-49-7.mol | [Molecular Weight]
1049.2 |
| Chemical Properties | Back Directory | [density ]
1.302±0.06 g/cm3(Predicted) | [pka]
-4.16±0.18(Predicted) | [Sequence]
Boc-{Tyr(SO3H)}-{Nle}-Gly-Trp-{Nle}-Asp-{2-Phenylethylamine} |
| Hazard Information | Back Directory | [Description]
Jmv 167 is a Cholecystokinin receptor antagonist. | [Uses]
JMV 167 is antagonist of peripheral cholecystokinin receptor (CKK), with an IC50 of 500 nM[1]. | [References]
[1] C Nagain, et al. Synthetic CCK8 analogs with antagonist activity on pancreatic receptors: in vivo study in the rat, compared to non-peptidic antagonists. Pancreas. 1991 May;6(3):275-81. DOI:10.1097/00006676-199105000-00004 |
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