| Identification | Back Directory | [Name]
DBCO-(CH2)3-Acid | [CAS]
1207355-31-4 | [Synonyms]
DBCO acid 2
DBCO-C5-acid
CAS_1207355-31-4
DBCO-(CH2)3-Acid
Dibenz[b,f]azocine-5(6H)-pentanoic acid, 11,12-didehydro-δ-oxo- | [Molecular Formula]
C20H17NO3 | [MDL Number]
MFCD30748340 | [MOL File]
1207355-31-4.mol | [Molecular Weight]
319.35 |
| Chemical Properties | Back Directory | [Boiling point ]
635.5±55.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [solubility ]
DMSO : 100 mg/mL (313.14 mM; Need ultrasonic) | [form ]
Solid | [pka]
4.63±0.10(Predicted) | [color ]
Off-white to brown |
| Hazard Information | Back Directory | [Uses]
DBCO-C3-Acid is a Click Chemistry intermediate used in the synthesis of antibody-drug conjugate (ADC) linker[1]. | [References]
[1] van Geel R, et al. Chemoenzymatic Conjugation of Toxic Payloads to the Globally Conserved N-Glycan of Native mAbs Provides Homogeneous and Highly Efficacious Antibody-Drug Conjugates. Bioconjug Chem. 2015;26(11):2233-2242. DOI:10.1021/acs.bioconjchem.5b00224 |
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| Company Name: |
Twochem Co.Ltd.
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021-58111628 15800915896 |
| Website: |
cn.twochem.com |
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