Identification | Back Directory | [Name]
Cytarabine triphosphate trisodium | [CAS]
1179343-17-9 | [Synonyms]
Ara CTP Sodium Salt Cytarabine triphosphate trisodium 2(1H)-Pyrimidinone, 4-amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-arabinofuranosyl]-, sodium salt (1:3) (ACI) | [Molecular Formula]
C9H13N3Na3O14P3 | [MOL File]
1179343-17-9.mol | [Molecular Weight]
507.15 |
Hazard Information | Back Directory | [Uses]
Cytarabine triphosphate (Ara-CTP) trisodiu, an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate trisodiu levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine[1]. | [References]
[1] Anderson E, et, al. Intracellular cytarabine triphosphate in circulating blasts post-treatment predicts remission status in patients with acute myeloid leukemia. Exp Hematol. 2019 Jun;74:13-18.e3. DOI:10.1016/j.exphem.2019.04.005 |
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